Jay Pritchett: God knows I couldn't love them more, but even the Kennedy's didn't get together this often.
Rob Petrie: I want to take a nap before I go to sleep.
Dr. Meredith Grey: At some point, you have to make a decision. Boundaries don't keep other people out. They fence you in. Life is messy. That's how we're made. So, you can waste your lives drawing lines. Or you can live your life crossing them. But there are some lines that are way too dangerous to cross.
Coach Toomey: Actually, Burdett never made the team.
Carl Kolchak: No?
Coach Toomey: You see, his butterfly stroke was like an effeminate moth.
Carlos: You know who you are, Gaby? You're the kind of person who would have turned away Mary and Joseph from the inn.
Gabrielle: Well, they should have called ahead.
Cartman Gets an Anal Probe - S1-E2
Cartman: How come everything today has involved things either coming in or going out of my ass?
Nick Miller: You're a freaking gold digger, Jess.
Jess: Do you think that if I were a gold digger, I'd be interested in you? I would be the worst gold digger in the world.
Hank Moody: You're so beautiful you're almost ugly.
Nathan Stark: Good job, Carter... Wow, that didn't even leave a bad taste in my mouth.
Marshall Jack Carter: Wait for it.
Nathan Stark: ...Oh, there it is.
Darrin Stephens: Sam, don't expect your mother to be gracious. She doesn't do imitations.
Grace: My love for you is like this scar. Ugly, but permanent.
Earthanasia AKA The End of the World Show - S7-E6
Bill: Christmases come, Christmases go. They're all the ruddy same - no one ever remembers them.