Doom (2005)

Pinky: You don't look like a "Mac."
Mac: Katsuhiko Kumanosuke Takaashi.
Pinky: So, Mac.

Corporal Dean Portman: I'm gonna lock myself in a motel room with a bottle of tequila and three she-boys.

Sarge: Semper Fi, Motherfucker! Faithful to the corps John.

Sarge: Kill them all, let God sort them out.

Sarge: Eliminate the threat.
The Kid: What threat?
Duke: It goes that this see, if its trying kill ya. Its a threat.

Sarge: I've got one round.

The Kid: Is it always that rough?
Pinky: Believe me, it used to be a lot rougher. There was a time when Ark travel was susceptible to, let's say major turbulence.
The Kid: What's he mean?
John Grimm: He means he went to one galaxy, his ass went to another.
Pinky: Call it a scientific miscalculation.

John Grimm: Like The Kid said, "Go to Hell".

Pinky: Portman, I got floor and wall on your gun cam.
Corporal Dean Portman: I'm taking a shit, you fucking gimp.

Corporal Dean Portman: Ladies, we're under a Level 5 quarantine so I'm gonna have to strip search you girls.

Samantha Grimm: 10% of the human genome is still unmapped. Some say it's the genetic blueprint for the soul.

Corporal Dean Portman: I don't believe this shit. Six months without a weekend, and the goddamn transporters are five minutes late. Now that's 5 minutes of R and R that I ain't gonna get back.
Duke: Relax baby, we're on vacation.