Factual error: Toward the end of the film, the nuns convince a helicopter pilot to fly them to Reno to rescue Sr. Mary Clarence (Whoopi Goldberg). The helicopter is a Bell Long Ranger. Twelve nuns depart the aircraft in Reno. There is no way that aircraft can hold that many people in addition to the pilot. It never would have gotten off the ground in San Francisco.

Factual error: At the very end of the movie, the Pope gives the nuns a standing ovation. The other people seated in the box with him should have immediately risen at this time. Instead, the man seated to his left looks up at him, seeing that the pontiff has stood, but makes no movement to join him on his feet.

Continuity: When storming to Eddie's office in the beginning of the movie, Deloris was no where near the door (a full 8 seconds away) when Eddie made the "Say goodnight, Ernie" statement so she couldn't have heard it, yet when she is talking to the police she includes that in her story.

Continuity: When Whoopi first takes over the choir, she asks the sisters to stand according to their singing voices. She asks where the sopranos are, and several women on opposite corners of the grouping raise their hands. She asks them to all move over to the left group, but only one of the two women on the right side actually does so.

Visible crew/equipment: When Eddie arrives at the casino near the end of the film, he opens the car door and in the reflection you can see the filming crew.

Continuity: When the choir are singing the first song that Deloris helps them with, Sister Mary Robert gains confidence and sings louder. Toward the end of the song, she puts her hands together in a praying gesture while she is singing loudly, but in the next shot her arms are by her side.

Other: During the 'Rescue Me' montage, when Maggie Smith catches Whoopi Goldberg singing whilst washing the car, Whoopi reacts to her and then there's a brief moment where she looks straight at the camera.