RoboCop's 'robovision' interface has references to MS-DOS, and RoboCop 2's 'robovision' interface has references to Apple Mac.

RoboCop 2 had the 2nd highest body count for a film in 1990, with 58 deaths. It was beaten only by Die Hard 2, with 162 deaths. (They cheated by having an aeroplane blow up, of course).

The auditorium used for the scenes at the end of the film was the George R. Brown Convention Center in Houston, Texas.

When Robocop hosts the raid at the arcade, most of the game machines have advertisements for the Data East software company. Data East made the Robocop video games.

The abandoned hospital used in RoboCop 2 for Cain's death and brain removal scenes was the former Jefferson Davis Hospital in Houston, Texas. The building was demolished in 1999, and the property where the hospital was once located was sold off to the U.S Federal Reserve for $23 million.

When Robocop's being reprogrammed, various information flashes up on screen, only really readable if watched frame by frame on a DVD. Various new directives come up, including 'Avoid Orion meetings' (Orion being the company that made the film). The names Kuran and Lockwood are shown among the garbage, being Peter Kuran and George Lockwood, two of the special effects team. There's also a string of numbers, which when treated as Hex and translated to ASCII comes out as 'Pete Kuran is a great guy'.

When Robocop picks up Duffy the dirty cop and throws him into the arcade machine, when Robocop then pulls him away from the screen, you can see that the game playing on the arcade is none other than Robocop.

At the start of the film when the gang break into the weapons store we see two of them argue about the cops coming to get them. If you look closely at the gun rack on the far left of the screen you will see a Beretta M93R-AG gun. This is the slightly unmodified version of the Auto-9 gun that RoboCop uses.

The Nuke drug holders are actually old tape cassette holders. The small capsule containing the Nuke is actually applicators for the drops that go on contact lenses, with water and red food colouring in them.

When Cain escapes from the drug factory at the beginning of the film, he shoots a Chinese woman who is hiding in his car. She was actually speaking real Mandarin to him and she said, "Take me with you, if not the police will catch me."

The films screenwriter Frank Miller makes a cameo appearance in the film. He plays the part of Frank, Cain's drug maker.

The films director, Irvin Kershner, appears in the film. When Dr. Faxx is screening candidates for the RoboCop 2 brain, the very first face seen on the screen is that of Irvin's.

While producers loved Frank Miller's original version of the script, they quickly realized it was unfilmable as written. The final screen version was heavily rewritten and bears only a superficial resemblance to Miller's story. In 2003, Miller's screenplay was adapted into a comic book series titled, appropriately, "Frank Miller's RoboCop".